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dc.contributor.authorTirado-Pérez, Irina Suleyspa
dc.contributor.authorZárate-Vergara, Andrea Carolinaspa
dc.date.accessioned2020-10-27T14:19:26Z
dc.date.available2020-10-27T14:19:26Z
dc.date.issued2018-07-06
dc.identifier.issn2382-4603
dc.identifier.issn0123-7047
dc.identifier.urihttp://hdl.handle.net/20.500.12749/9962
dc.description.abstractIntroducción: La anemia falciforme es una hemoglobinopatía estructural de origen genético, se caracteriza por la presencia de hemoglobina falciforme. La hemoglobina anormal es inestable, tiende a polimerizarse y puede ocluir la microcirculación, produciendo manifestaciones multisistémicas tanto agudas como crónicas relacionándose con mayor riesgo de contraer infecciones. Objetivo: Describir la información del tema expuesto resaltando los aspectos más relevantes como diagnóstico y tratamiento. Metodología: Se efectuó una revisión bibliográfica con búsqueda electrónica en las siguientes bases de datos: PubMed, MEDLINE, Medscape, Scopus; y se incluyó diferentes tipos de artículo (artículos originales, revisiones de temas y guías de manejo) que abordaran la anemia de células falciformes en pediatría. Resultados: Se obtuvo una revisión de 22 artículos, donde se describe el tema de anemia de células falciformes, pautas y tratamientos basados en el manejo y control de los síntomas; se evidencia que el uso de ecografía doppler transcraneal y las transfusiones demostraron ser estrategias preventivas o de tratamiento eficaces para las complicaciones relacionadas con esta patología en los niños. Conclusiones: En Colombia, la prevalencia de la patología no se encuentra establecida. Por otra parte, las principales manifestaciones se relacionan con complicaciones de vaso-oclusión en los diferentes órganos y la asplenia funcional, la cual predispone a cuadros infecciosos. [Tirado-Pérez IS, Zárate Vergara AC. Anemia de células falciformes en pediatría: Revisión de la literatura. Revisión de tema. MedUNAB 2017-2018; 20(3): 374-382].spa
dc.format.mimetypeapplication/pdfspa
dc.language.isospaspa
dc.publisherUniversidad Autónoma de Bucaramanga UNAB
dc.relationhttps://revistas.unab.edu.co/index.php/medunab/article/view/2378/2862
dc.relation/*ref*/Maakaron J, Taher A. Sickle Cell Anemia. Medscape article. [Internet]. 2015. [Updated: Oct 15, 2015]. Disponible en: http://emedicine.medscape.com/article/205926-overview 2. Quintero M, Jiménez A. Anemia De Células Falciformes. Revista Gastrohnup. 2012; 14(2):Sup1:S27-S35. 3. Ayala A, González H, David G. Anemia de células falciformes: una revisión. Salud Uninorte. 2016; 32(3):513-527. 4. Kavanagh P, Sprinz P, Vinci S, Bauchner H, Wang C. Management of Children With Sickle Cell Disease: A Comprehensive Review of the Literature. Pediatrics. 2011; 128(6):1552-1574. 5. Lemanek K, Ranalli M, Lukens C. A randomized controlled trial of massage therapy in children with sickle cell disease. J Pediatr Psychol. 2009; 34(10):1091–1096. 6. McClellan C, Schatz J, Puffer E, Sanchez C, Stancil M, Roberts C. Use of handheld wireless technology for a home-based sickle cell pain management protocol. J Pediatr Psychol. 2009; 34(5):564–573. 7. Nolan V, Zhang Y, Lash T, Sebastiani P, Steinberg M. Association between wind speed and the occurrence of sickle cell acute painful episodes: results of a casecrossover study. Br J Haematol. 2008; 143(3):433–8. 8. Meier E, Miller J. Sickle cell disease in children. Drugs. 2012; 72(7):895-906. 9. Sparkenbaugh E, Pawlinski R. Prothrombotic aspects of sickle cell disease. J Thromb Haemost. 2017; 15(7):1307–16. 10. Cervera Á, Cela E. Anemia falciforme. Manejo en Atención Primaria. Rev Pediatr Aten Primaria. 2007; 9(36):649-68. 11. Driscoll M, Hurlet A, Styles L, Mckie V, Files B, et al. Stroke risk in siblings with sickle cell anemia. Blood. 2003; 101(6):2401-2404. 12. Yazdanbakhsh K, Shaz B, Hillyer C. Immune regulation of sickle cell alloimmunization. ISBT Science Series. 2017; 12(1):248–253. Disponible en: https://doi.org/10.1111/voxs.12296. 13. National Heart, Lung, and Blood Institute. Management and therapy of sickle cell disease. 4ed. Bethesda. [Internet]. 2002. [Revisado el: Oct 15, 2015]. Disponible en: https://www.nhlbi.nih.gov/files/docs/guidelines/sc_mngt.pdf 14. American Academy of Pediatrics, Section on Hematology/Oncology and Committee on Genetics. Health supervision for children with sickle cell disease. Pediatrics. 2002; 109(3):526-35. 15. Adams R, McKie V, Hsu L, Files B, Vichinsky E, et al. Prevention of a First Stroke by Transfusions in Children with Sickle Cell Anemia and Abnormal Results on Transcranial Doppler Ultrasonography. N Engl J Med. 1998; 339:5-11. 16. Yawn B, Buchanan G, Afenyi-Annan A, et al. Management of Sickle Cell Disease: Summary of the 2014 Evidence-Based Report by Expert Panel Members. JAMA. 2014; 312(10):1033-1048. Disponible en: https://doi.org/10.1001/Jama.2014.10517. 17. Adams R, Brambilla D, Granger S, Gallagher D, Vichinsky E, et al. Stroke and Conversion To High Risk In Children Screened With Transcranial Doppler Ultrasound During The STOP Study. Blood. 2004; 103(10):3689-3694. 18. Vichinsky E, Neumayr L, Earles A, Williams R, Lennette E, et al. Causes and outcomes of the acute chest syndrome in sickle cell disease. N Engl J Med. 2000; 342(25):1855–1865. 19. Morris C, Vichinsky E, Styles L. Clinician assessment for acute chest syndrome in febrile patients with sickle cell disease: is it accurate enough?. Ann Emerg Med. 1999; 34(1):64–69. 20. Smith K, Zhao H, Hodinka RL, et al. Epidemiology of human parvovirus B19 in children with sickle cell disease. Blood. 2004; 103(2):422–427. 21. Gil K, Carson J, Porter L, Ready J, Valrie C, et al. Daily stress and mood and their association with pain, health-care use, and school activity in adolescents with sickle cell disease. J Pediatr Psychol. 2003; 28(5):363–373. 22. Jacob E, Miaskowski C, Savedra M, Beyer J, Treadwell M, Styles L. Management of vaso-occlusive pain in children with sickle cell disease. J Pediatr Hematol Oncol. 2003; 25(4):307–311.
dc.relation.urihttps://revistas.unab.edu.co/index.php/medunab/article/view/2378
dc.sourceMedUNAB; Vol. 20 Núm. 3 (2018): Diciembre - Marzo de 2018: Educación, Tabaquismo, Accidente Ofídico; 374-382
dc.subjectAnemia Hemolítica
dc.subjectAnemia de Células Falciformes
dc.subjectHemoglobina Falciforme
dc.subjectPediatría
dc.subjectEnfermedad de la Hemoglobina SC
dc.titleAnemia de células falciformes en pediatría: Revisión de la literatura
dc.title.translatedSickle Cell Anemia in Pediatrics: Literature review
dc.type.driverinfo:eu-repo/semantics/article
dc.type.localArtículospa
dc.type.coarhttp://purl.org/coar/resource_type/c_7a1f
dc.subject.keywordsAnemia, Hemolyticeng
dc.subject.keywordsAnemia, Sickle Celleng
dc.subject.keywordsHemoglobin, Sickleeng
dc.subject.keywordsPediatricseng
dc.subject.keywordsHemoglobin SC Diseaseeng
dc.identifier.instnameinstname:Universidad Autónoma de Bucaramanga UNABspa
dc.type.hasversionInfo:eu-repo/semantics/publishedVersion
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.identifier.repourlrepourl:https://repositorio.unbosque.edu.co
dc.description.abstractenglishIntroduction: Sickle cell anemia is a structural hemoglobinopathy of genetic origin, characterized by the presence of sickle hemoglobin. Abnormal hemoglobin is unstable and tends to polymerize and can occlude the microcirculation. Also, it produces both acute and chronic multi system manifestations associated with an increased risk of infection. Objective: To describe the information of the exposed topic highlighting the most relevant aspects such as diagnosis and treatment. Methodology: A literature review with electronic search was carried out in the following databases: PubMed, MEDLINE, Medscape, Scopus; different types of articles were included that addressed sickle cell anemia in pediatrics such as original articles, reviews of topics and management. Results: A review of 22 articles was obtained which describes the subject of sickle cell anemia, guidelines and treatments based on the management and control of symptoms. It is evident that the use of transcranial Doppler ultrasound and transfusions proved to be preventive strategies or effective treatments for the complications related to this pathology in children. Conclusions: In Colombia, the prevalence of the pathology is not established yet. On the other hand, the main manifestations are related to complications of vaso-occlusion in different organs and functional asplenia which predisposes to infectious conditions. [Tirado-Pérez IS, Zárate Vergara AC. Sickle Cell Anemia in Pediatrics: Literature review. MedUNAB 2017-2018; 20(3): 374-382].eng
dc.identifier.doi10.29375/01237047.2378
dc.type.redcolhttp://purl.org/redcol/resource_type/CJournalArticle
dc.rights.creativecommonsAtribución-NoComercial-SinDerivadas 2.5 Colombia*


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