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dc.contributor.authorPorras-Alvarez, Javierspa
dc.date.accessioned2020-10-27T14:19:24Z
dc.date.available2020-10-27T14:19:24Z
dc.date.issued2018-11-19
dc.identifier.issn2382-4603
dc.identifier.issn0123-7047
dc.identifier.urihttp://hdl.handle.net/20.500.12749/9955
dc.description.abstractIntroducción. La fatiga central en el deporte está asociada a los efectos del amonio. La principal fuente de producción de amonio durante el ejercicio es el músculo esquelético. El amonio se genera como consecuencia del metabolismo energético, debido a la oxidación de aminoácidos y a la desaminación del nucleótido de adenosin trifosfato. Objetivo. Presentar una reflexión sobre el efecto del amonio durante el ejercicio de alta intensidad y su relación con la fatiga central en atletas. Discusión. Durante el ejercicio, la concentración de amonio alcanza valores superiores a 200µM (micromolar); sin embargo, en un adulto promedio se considera que valores superiores a 60µM en sangre manifiestan un trastorno por hiperamonemia. El amonio influye en la disminución del rendimiento en atletas y está asociado con los efectos nocivos para la salud en pacientes con encefalopatía hepática. Conclusiones. La práctica del ejercicio físico genera neuroprotección contra las altas concentraciones de amonio en el cerebro, pues, durante el ejercicio con altas concentraciones de amonio, los atletas no presentan los síntomas de pacientes con encefalopatía hepática, lo que implica adaptaciones metabólicas que juegan un papel importante en el metabolismo del amonio en el cerebro. [Porras-Álvarez J. Consecuencias del amonio en la fatiga central en atletas, posible efecto neuroprotector del ejercicio. MedUNAB. 2018;21(1):xx-xx. doi: 10.29375/01237047.xxxx].spa
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dc.language.isospaspa
dc.publisherUniversidad Autónoma de Bucaramanga UNAB
dc.relationhttps://revistas.unab.edu.co/index.php/medunab/article/view/3394/2886
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dc.relation.urihttps://revistas.unab.edu.co/index.php/medunab/article/view/3394
dc.sourceMedUNAB; Vol. 21 Núm. 1 (2018): Abril - julio 2018: Topografía de la Córnea, Indicadores Bibliométricos, Calidad de Vida; 115-121
dc.subjectFatiga
dc.subjectCompuestos de Amonio Cuaternario
dc.subjectEntrenamiento de Resistencia
dc.subjectEjercicio
dc.subjectSistema Inmunológico
dc.subjectÁcido Úrico
dc.subjectEncefalopatía Hepática
dc.titleConsecuencias del amonio en la fatiga central en atletas, posible efecto neuroprotector del ejercicio
dc.title.translatedAmmonium consequences in athletes’ central fatigue and its possible neuroprotection effect thanks to physical activity
dc.type.driverinfo:eu-repo/semantics/article
dc.type.localArtículospa
dc.type.coarhttp://purl.org/coar/resource_type/c_7a1f
dc.subject.keywordsFadigaeng
dc.subject.keywordsCompostos de Amônio Quaternárioeng
dc.subject.keywordsTreinamento de Resistênciaeng
dc.subject.keywordsExercícioeng
dc.subject.keywordsSistema Imunitárioeng
dc.subject.keywordsÁcido Úricoeng
dc.subject.keywordsEncefalopatia Hepáticaeng
dc.identifier.instnameinstname:Universidad Autónoma de Bucaramanga UNABspa
dc.type.hasversionInfo:eu-repo/semantics/publishedVersion
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.identifier.repourlrepourl:https://repository.unab.edu.co
dc.description.abstractenglishIntroduction. Central fatigue in sports training is associated with ammonium effects within the human body. The ammonium main production source during physical training is located in skeletal muscles and it is generated as a result of energy metabolism. This process is caused by amino acids oxidation and adenosine triphosphate nucleotide deamination. Objective. This article’s objective is to present an analysis regarding ammonium effects when high intensity sports are performed and its relation with central fatigue in athletes. Discussion. When high intensity sport practices are performed, ammonium concentration levels can reach values higher than 200 µM (micromolar). However, it is considered that an average adult with ammonium levels higher than 60µM evidences a hyperammonemia disorder. Ammonium has direct influence in the decline of athletic performance and it is associated with harmful effects for hepatic encephalopathy patients. Conclusions. Physical activity practice creates neuroprotection against high-quantities of ammonium in the brain. Although in physical practices athletes have high amounts of ammonium, they do not show symptoms related to hepatic encephalopathy; thus, this situation implies that metabolic adaptations have an important role within ammonium metabolism in the brain. [Porras-Álvarez J. Ammonium consequences in athletes’ central fatigue and its possible neuroprotection effect thanks to physical activity. MedUNAB. 2018;21(1):xx-xx. doi: 10.29375/01237047.xxxx].eng
dc.identifier.doi10.29375/01237047.3394
dc.type.redcolhttp://purl.org/redcol/resource_type/CJournalArticle
dc.rights.creativecommonsAtribución-NoComercial-SinDerivadas 2.5 Colombia*


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