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dc.contributor.advisorCastellanos Domínguez, Yeny Zulay
dc.contributor.advisorOsma Zambrano, Sonia Esperanza
dc.contributor.authorNova Herrera, Nathalia Andrea
dc.coverage.spatialFloridablanca (Santander, Colombia)spa
dc.date.accessioned2020-10-22T20:48:17Z
dc.date.available2020-10-22T20:48:17Z
dc.date.issued2020
dc.identifier.urihttp://hdl.handle.net/20.500.12749/7316
dc.description.abstractIntroducción: La pielonefritis aguda definida como bacteriuria significativa asociada a inflamación del parénquima, los cálices y/o la pelvis renales, es la complicación infecciosa más frecuente durante el embarazo y la primera causa de hospitalización de origen no obstétrico. Objetivo: Determinar la incidencia de pielonefritis aguda en el embarazo, tasa de curación microbiológica y resultados maternos en gestantes hospitalizadas en la clínica Foscal en Floridablanca, Colombia. Materiales y métodos: Estudio observacional con una cohorte cerrada de gestantes con diagnóstico clínico de pielonefritis aguda y urocultivo positivo. Los datos presentados tuvieron una estimación con un nivel de confianza del 95%. Para el análisis de los datos se usó el paquete estadístico STATA 14.0. Resultados: Se incluyeron 50 gestantes hospitalizadas en el servicio de obstetricia de la clínica Foscal en el 2018. Se estimó una incidencia de 19,8 casos por cada 1.000 nacimientos año, se aislaron Escherichia coli BLEE- y Klebsiella pneumoniae BLEE- en un 62% y 10% respectivamente. La tasa de curación microbiológica fue de 4,6 casos de pielonefritis aguda por cada 100 días de seguimiento, IC 95% (3,4-6,2) y la tasa de persistencia fue de 5,6 casos por cada 100 días de seguimiento, IC 95% (2,1-12,4). La amenaza de parto pretérmino se presentó en el 8% de los casos. Conclusión: La pielonefritis aguda durante el embarazo ha sido considerada como una importante causa de morbilidad materna y perinatal. A través de esta investigación se documentó la incidencia de esta patología en la Clínica Foscal. Igualmente, se describieron las características de la población estudiada y los resultados maternos asociados a este problema de salud. Se descata como el primer estudio tanto local y como nacional que intentó determinar los factores asociados a la curación microbiológica.spa
dc.description.tableofcontents1. RESUMEN DEL PROYECTO ……………………………………… 8 2. INTRODUCCIÓN …………………………………………………….. 12 3. PLANTEAMIENTO DEL PROBLEMA ……………………………. 13 4. JUSTIFICACIÓN …………………………………………………….. 13 5. MARCO TEÓRICO ………………………………………………….. 5.1 Estado del arte …………………………………………………... 14 34 6. PROTOCOLO DE INVESTIGACIÓN ……………………………… 6.1 Pregunta de investigación ……………………………………… 6.2 Objetivo general …………………………………………………. 6.3 Objetivos específicos …………………………………………… 6.4 Metodología ……………………………………………………… 6.4.1 Diseño epidemiológico ……………………………………….. 6.4.2 Población a estudio ………………………………………….. 6.4.3 Criterios de inclusión …………………………………………. 6.4.4 Criterios de exclusión ………………………………………… 6.5 Cálculo de la muestra y muestreo …………………………….. 6.6 Procedimiento …………………………………………………… 6.8 Depuración de datos y plan de análisis ………………………. 6.9 Operacionalización de las variables …………………………... 40 40 40 41 41 41 41 42 42 42 42 45 47 7. DISPOSICIONES VIGENTES ……………………………………… 47 8. RESULTADOS ………………………………………………………. 50 9. DISCUSIÓN ………………………………………………………….. 70 10. CONCLUSIÓN ……………………………………………………….. 77 11. BIBLIOGRAFÍA ……………………………………………………… 79spa
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dc.language.isospaspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/*
dc.titleIncidencia de pielonefritis aguda en el embarazo, tasa de curación microbiológica y resultados maternos en la Clínica Foscal Floridablanca, Colombiaspa
dc.title.translatedIncidence of acute pyelonephritis in pregnancy, microbiological cure rate and maternal outcomes at the Foscal Floridablanca Clinic, Colombiaspa
dc.degree.nameEspecialista en Ginecología y Obstetriciaspa
dc.publisher.grantorUniversidad Autónoma de Bucaramanga UNABspa
dc.rights.localAbierto (Texto Completo)spa
dc.publisher.facultyFacultad Ciencias de la Salud
dc.publisher.programEspecialización en Ginecología y Obstetricia
dc.description.degreelevelEspecializaciónspa
dc.type.driverinfo:eu-repo/semantics/masterThesis
dc.type.localTesisspa
dc.type.coarhttp://purl.org/coar/resource_type/c_7a1f
dc.subject.keywordsGynecologyspa
dc.subject.keywordsObstetricsspa
dc.subject.keywordsMedical sciencesspa
dc.subject.keywordsHealth sciencesspa
dc.subject.keywordsPyelonephritisspa
dc.subject.keywordsPregnancyspa
dc.subject.keywordsIncidencespa
dc.subject.keywordsColombiaspa
dc.subject.keywordsMedical practicespa
dc.subject.keywordsKidney diseasespa
dc.identifier.instnameinstname:Universidad Autónoma de Bucaramanga - UNAB
dc.identifier.reponamereponame:Repositorio Institucional UNAB
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersion
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2
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dc.contributor.cvlachttps://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0000660280spa
dc.contributor.googlescholarhttps://scholar.google.es/citations?hl=es&user=hToq6yMAAAAJspa
dc.contributor.orcidhttps://orcid.org/0000-0003-4450-3147spa
dc.contributor.scopushttps://www.scopus.com/authid/detail.uri?authorId=36477836200spa
dc.subject.lembGinecologíaspa
dc.subject.lembObstetriciaspa
dc.subject.lembCiencias médicasspa
dc.subject.lembPráctica médicaspa
dc.subject.lembEnfermedades renalesspa
dc.identifier.repourlrepourl:https://repository.unab.edu.cospa
dc.description.abstractenglishIntroduction: Acute pyelonephritis, defined as significant bacteriuria associated with inflammation of the parenchyma, calyces and/or renal pelvis, is the most frequent illness found during pregnancy due to its infectious base and becoming the first cause of hospitalization owing to its non-obstetric origin. Objective: To determine the frequency of acute pyelonephritis during pregnancy, microbiological cure rate and maternal outcomes in pregnant women hospitalized at the Foscal Clinic in Floridablanca, Colombia. Materials and methods: Observational study with a closed cohort of 50 pregnant women diagnosed with acute pyelonephritis. The data presented, had an estimate with a confidence level of 95%. For the analysis of the outcome, the statistical package STATA 14.0 was used. Results: Fifty pregnant women hospitalized in the obstetrics service of the Foscal Clinic in 2018 were included in the research. An incidence of 19.8 cases per 1,000 births per year was estimated, the most frequently isolated germs were Escherichia coli and Klebsiella pneumoniae in 62% and 10% respectively. The microbiological cure rate was 4.6 cases of acute pyelonephritis was found for every 100 days of followup, 95% CI (3,4-6,2) and a microbiological persistence rate of 5,6 cases for every 100 days of follow-up, 95% CI (2,1-12,4). The preterm labor ocurred in 8% of cases. Conclusion: Acute pyelonephritis during pregnancy has been considered an important cause of maternal and perinatal morbidity. Through this research, the incidence of this pathology at the Foscal Clinic was documented. The characteristics of the study population and the maternal outcomes associated with this health problem were also described. It is ruled out as the first study, both local and national, that attempted to determine the factors associated with microbiological cure.spa
dc.subject.proposalCiencias de la saludspa
dc.subject.proposalPielonefritisspa
dc.subject.proposalEmbarazospa
dc.subject.proposalIncidenciaspa
dc.subject.proposalColombiaspa
dc.subject.proposalClínica Foscalspa
dc.rights.creativecommonsAtribución-NoComercial-SinDerivadas 2.5 Colombia*


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