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Calidad de vida de pacientes adultos con hemofilia del nororiente colombiano, proyecto anidado al estudio “baja densidad mineral ósea y osteoporosis en pacientes con hemofilia"
dc.contributor.advisor | Sossa Melo, Claudia Lucía | spa |
dc.contributor.advisor | Ochoa Vera, Miguel Enrique | spa |
dc.contributor.author | Ortiz Becerra, Mayra Lizbeth | spa |
dc.date.accessioned | 2020-06-26T19:59:56Z | |
dc.date.available | 2020-06-26T19:59:56Z | |
dc.date.issued | 2017 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12749/1747 | |
dc.description.abstract | Métodos: Mediante un estudio descriptivo analítico tipo corte transversal, se evaluó la calidad de vida relacionada con la salud (CVRS) en 56 pacientes en la FOSCAL, mediante la aplicación del cuestionario Hemolatin QoL. Resultados: Estudio descriptivo, corte transversal, 56 pacientes, 89,29% con diagnóstico de Hemofilia tipo A, y 10,71% de Hemofilia tipo B. En términos de severidad, el 60,71% con hemofilia severa, 21,43% con hemofilia moderada y 17,86% con hemofilia leve. El Índice de calidad de vida promedio encontrado en nuestros pacientes Hemofílicos de forma global fue de 71,08 puntos, equivalente en promedio al 60 – 70%, lo que engloba a los pacientes en regular y mejorable calidad de vida, la mayor afectación observada en condiciones del entorno y salud mental. Los Hemofílicos severos y moderados tienen mayor compromiso en el índice de calidad de vida (62,60% y 64,66%), respectivamente en comparación con los Hemofílicos leves (78,15%) con (p=<0,01 y p=0,02 respectivamente). En cuanto a sangrado en los últimos 12 meses, presencia de complicaciones como positividad de inhibidores, coinfección por VIH, Hepatitis C, Artropatía hemofílica no se encontraron diferencias significativas que influyeran en la calidad de vida los individuos. La mayoría de los pacientes se encontraban recibiendo manejo actual con profilaxis, sin embargo no se encontraron diferencias estadísticamente significativas con los pacientes que recibían factor a demanda, excepto para la dimensión de salud mental, presentado menor afectación para los que se encuentran con factor a demanda con una (p 0,02). En cuanto al nivel de actividad física medida con la escala GPAQ encontramos que los pacientes que tenían un nivel de actividad física alta tenían un mayor índice de CV 68,90% (IC 62,57% –75,2%) con respecto a lo que tenían un nivel de actividad baja; siendo esta diferencia significativa con una (p=0,03). Se encontró una asociación con una muy mala calidad de vida en el dominio de funcionamiento emocional con los pacientes que presentaban Baja densidad mineral ósea para la edad con una RP de 4,4 con (IC 1,05- 18,31) con una p de 0,04. | spa |
dc.format.mimetype | application/pdf | spa |
dc.language.iso | spa | spa |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/2.5/co/ | * |
dc.title | Calidad de vida de pacientes adultos con hemofilia del nororiente colombiano, proyecto anidado al estudio “baja densidad mineral ósea y osteoporosis en pacientes con hemofilia" | spa |
dc.title.translated | Quality of life of adult patients with hemophilia from the colombian northeast, project nested in the study "low bone mineral density and osteoporosis in patients with hemophilia | eng |
dc.degree.name | Especialista en Medicina Interna | spa |
dc.coverage | Bucaramanga (Santander, Colombia) | spa |
dc.publisher.grantor | Universidad Autónoma de Bucaramanga UNAB | spa |
dc.rights.local | Abierto (Texto Completo) | spa |
dc.publisher.faculty | Facultad Ciencias de la Salud | spa |
dc.publisher.program | Especialización en Medicina Interna | spa |
dc.description.degreelevel | Especialización | spa |
dc.type.driver | info:eu-repo/semantics/masterThesis | |
dc.type.local | Tesis | spa |
dc.type.coar | http://purl.org/coar/resource_type/c_bdcc | |
dc.subject.keywords | Quality of life | eng |
dc.subject.keywords | Hemophilia | eng |
dc.subject.keywords | Bone mineral density | eng |
dc.subject.keywords | Osteoporosis | eng |
dc.subject.keywords | Medicine | eng |
dc.subject.keywords | Internal medicine | eng |
dc.subject.keywords | Investigations | eng |
dc.subject.keywords | Complications | eng |
dc.subject.keywords | Patients | eng |
dc.subject.keywords | Prevention and control | eng |
dc.subject.keywords | Symptoms | eng |
dc.subject.keywords | Exercise physical | eng |
dc.subject.keywords | Hemophilic patients | eng |
dc.subject.keywords | Risk of fractures | eng |
dc.identifier.instname | instname:Universidad Autónoma de Bucaramanga - UNAB | spa |
dc.identifier.reponame | reponame:Repositorio Institucional UNAB | spa |
dc.type.hasversion | info:eu-repo/semantics/acceptedVersion | |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.rights.accessrights | http://purl.org/coar/access_right/c_abf2 | spa |
dc.relation.references | Ortiz Becerra, Mayra Lizbeth (2017). Calidad de vida de pacientes adultos con hemofilia del Nororiente Colombiano, proyecto anidado al estudio “Baja densidad mineral ósea y osteoporosis en pacientes con Hemofilia. Bucaramanga (Santander, Colombia) : Universidad Autónoma de Bucaramanga UNAB | spa |
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dc.contributor.cvlac | https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0000898465;https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001425704 | * |
dc.contributor.cvlac | https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001512540 | * |
dc.contributor.orcid | https://orcid.org/0000-0002-4552-3388 | * |
dc.contributor.scopus | https://www.scopus.com/authid/detail.uri?authorId=36987156500;https://www.scopus.com/authid/detail.uri?authorId=57203553484 | * |
dc.contributor.researchgate | https://www.researchgate.net/profile/Miguel_Ochoa7;https://www.researchgate.net/profile/Claudia_Sossa?_sg=BvRoh6IvojFf2p-POYF__s50hoM8A_BUZv09EbDIIEubX8HzSQD8c55b5wN2DjEMJzlDAXO3X74Ci8Q | * |
dc.subject.lemb | Calidad de vida | spa |
dc.subject.lemb | Hemofilia | spa |
dc.subject.lemb | Densidad mineral ósea | spa |
dc.subject.lemb | Osteoporosis | spa |
dc.subject.lemb | Medicina | spa |
dc.subject.lemb | Medicina interna | spa |
dc.subject.lemb | Investigaciones | spa |
dc.subject.lemb | Complicaciones | spa |
dc.subject.lemb | Pacientes | spa |
dc.subject.lemb | Prevención y control | spa |
dc.description.abstractenglish | Methods: Through a cross-sectional analytical descriptive study, evaluated the Health-related Quality of Life (HRQoL) in 56 patients in the FOSCAL, by applying the Hemolatin QoL questionnaire. Results: Descriptive study, cross section, 56 patients, 89.29% with a diagnosis of Hemophilia type A, and 10.71% Hemophilia type B. In terms of severity, the 60.71% with severe hemophilia, 21.43% with moderate hemophilia, and 17.86% with mild hemophilia. The average quality of life index found in our Hemophiliac patients overall was 71.08 points, equivalent in average 60 - 70%, which includes patients in regular and improvable quality of life, the greatest damage observed in environmental and health conditions mental. Severe and moderate hemophiliacs have a greater commitment in the quality of life index (62.60% and 64.66%), respectively compared with mild hemophiliacs (78.15%) with (p = <0.01 and p = 0.02 respectively). In regarding bleeding in the last 12 months, presence of complications such as inhibitor positivity, HIV co-infection, Hepatitis C, Hemophilic arthropathy no significant differences were found that influenced the quality of life individuals. Most of the patients were receiving current management with prophylaxis, however no statistically differences were found significant with patients receiving factor on demand, except for mental health dimension, presenting less affectation for those who find a demand factor with a (p 0.02). Regarding the level of activity physical measurement with the GPAQ scale, we found that patients who had a high level of physical activity had a higher CV index 68.90% (CI 62.57% - 75.2%) with respect to those who had a low activity level; being this significant difference with one (p = 0.03). An association was found with a very poor quality of life in the domain of emotional functioning with patients who had low bone mineral density for age with a PR of 4.4 with (CI 1.05-18.31) with a p of 0.04. Conclusions: In the present study, the quality of life related to health with the Hemolatin QoL questionnaire in patients diagnosed with Foscal hemophilia, we show that the severity of hemophilia is related to the probability of having a regular and poor quality of life, with greater impact in the domains of environmental conditions and mental health. Patients who had a high level of physical activity measured by questionnaire GPAQ had a higher CV index with respect to what they had a level of low activity. Another important finding in our study was related to low bone mineral density for age detected in hemophilic patients associated with a higher risk of fractures, with a low quality of life index compared to those with normal BMD. In summary, the severity of hemophilia was shown to be a factor associated with a higher frequency of deterioration of quality of life, independently, and the BMI with CV protective factor according to multivariate analysis. | eng |
dc.subject.proposal | Síntomas | |
dc.subject.proposal | Actividad física | |
dc.subject.proposal | Pacientes hemofílicos | |
dc.subject.proposal | Riesgo de fracturas | |
dc.type.redcol | http://purl.org/redcol/resource_type/TM | |
dc.rights.creativecommons | Atribución-NoComercial-SinDerivadas 2.5 Colombia | * |
dc.contributor.researchgroup | Grupo de Investigaciones Clínicas | spa |
dc.coverage.campus | UNAB Campus Bucaramanga | spa |
dc.description.learningmodality | Modalidad Presencial | spa |