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dc.contributor.advisorUribe, Juan Carlosspa
dc.contributor.authorTorres Agredo, Liliana Patriciaspa
dc.date.accessioned2020-06-26T19:58:05Z
dc.date.available2020-06-26T19:58:05Z
dc.date.issued2015
dc.identifier.urihttp://hdl.handle.net/20.500.12749/1707
dc.description.abstractEl estudio de neoplasias óseas integra tres áreas médicas: ortopedia, radiología y patología. El ortopedista inicia el estudio con una historia clínica y examen físico completo donde genera una primera impresión diagnóstica, posteriormente complementa su investigación con estudios de imágenes de radiología convencional y especializada (radiografía, tomografía contrastada y resonancia nuclear magnética), lo cual permite la caracterización de las lesiones, definir localización, características al contraste que orienten al tipo de tumor y nivel de compromiso de los tejidos; por último, según los hallazgos se procede a la realización de una biopsia. La biopsia permite obtener una muestra de los tejidos músculo-esqueléticos que determinan la naturaleza de la lesión para identificar lesiones malignas o benignas lo cual orienta la conducta terapéutica definitiva (1). Se utilizan dos vías en la realización de la biopsia: abiertas (excisionales o incisionales) y percutánea (o por punción); esta última, puede realizarse mediante aguja gruesa, ya sea con Tru-Cut o agujas de hueso tipo core que extraen un cilindro; la biopsia de aguja fina también denominada BACAF es muy frecuentemente utilizada para carcinomas pero en lesiones musculoesqueléticas no es lo recomendado porque solo permite el análisis celular sin estroma. La decisión del tipo de biopsia de dependerá de la localización de la lesión, del diagnóstico diferencial y de la experiencia del patólogo (2). Al comparar ambos procedimientos, la biopsia abierta permite obtener mayor cantidad de tejido, con mayor confiabilidad y precisión, sin embargo es un procedimiento más costoso, se debe realizar en salas de cirugía con anestesiólogo, presenta mayor riesgo de fractura, de compromiso de tejidos periféricos, y complicaciones en la herida como infecciones, seromas, hematomas, dehiscencia de la herida, contaminación del tumor (3,4) . La biopsia percutánea, es un procedimiento mínimamente invasivo, se puede realizar en una sala de procedimientos, a un menor costo, presenta menor morbilidad con menor riesgo de complicaciones y permite la obtención de una adecuada cantidad de tejido para hacer el diagnóstico. Sin embargo requiere de un patólogo con experiencia.(5). El presente estudio, busca definir las características generales de los hallazgos histopatológicos en biopsias percutáneas y abiertas de un centro oncológico en ortopedia, así como explorar factores de riesgo para la conversión de una biopsia percutánea a abierta.spa
dc.description.tableofcontents1. INTRODUCCIÓN 7 2. PROBLEMA DEL ESTUDIO 8 2.1 Planteamiento del problema 8 2.2 Formulación del problema 8 3. JUSTIFICACIÓN 8 4. OBJETIVOS 9 4.1 Objetivo general 9 4.2 Objetivos específicos 9 5. MARCO TEÓRICO 9 5.1 Biopsia abierta 10 5.2 La biopsia percutánea 10 5.3 Indicaciones de la biopsia percutánea 10 5.4 Lesiones que no requieren biopsia 11 5.5 Contraindicaciones 11 5.6 Técnica de a biopsia percutánea 11 5.7 Tomografía axial computarizada 12 6. ASPECTOS METODOLÓGICOS 12 6.1 Tipo de estudio 12 6.2 Población de referencia y muestra 12 6.3 Operacionalización de variables (Tabla 1) 12 7. PROCEDIMIENTO 14 7.1 Control de calidad de los datos 14 8. ANÁLISIS ESTADÍSTICO 14 9. ASPECTOS ÉTICOS 14 10. RESULTADOS 15 11. DISCUSIÓN 22 12. CONCLUSIONES 24 13. REFERENCIAS 25spa
dc.format.mimetypeapplication/pdfspa
dc.language.isospaspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/*
dc.titlePrecisión diagnóstica de la biopsia percutánea en ortopedia oncológica en la obtención de diagnóstico histopatológico (reporte de casos)spa
dc.title.translatedDiagnostic accuracy of percutaneous biopsy in oncological orthopedics in obtaining a histopathological diagnosis (case report)eng
dc.degree.nameEspecialista en Epidemiologíaspa
dc.coverageBucaramanga (Santander, Colombia)spa
dc.publisher.grantorUniversidad Autónoma de Bucaramanga UNABspa
dc.rights.localAbierto (Texto Completo)spa
dc.publisher.facultyFacultad Ciencias de la Saludspa
dc.publisher.programEspecialización en Epidemiologíaspa
dc.description.degreelevelEspecializaciónspa
dc.type.driverinfo:eu-repo/semantics/masterThesis
dc.type.localTesisspa
dc.type.coarhttp://purl.org/coar/resource_type/c_bdcc
dc.subject.keywordsPercutaneous biopsyeng
dc.subject.keywordsOrthopedicseng
dc.subject.keywordsHistopathological diagnosiseng
dc.subject.keywordsMedicineeng
dc.subject.keywordsEpidemiologyeng
dc.subject.keywordsInvestigationseng
dc.subject.keywordsOncologicaleng
dc.subject.keywordsMedical areaseng
dc.subject.keywordsClinical historyeng
dc.identifier.instnameinstname:Universidad Autónoma de Bucaramanga - UNABspa
dc.identifier.reponamereponame:Repositorio Institucional UNABspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersion
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2spa
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dc.contributor.orcidhttps://orcid.org/0000-0002-1295-7796*
dc.subject.lembBiopsia percutáneaspa
dc.subject.lembOrtopediaspa
dc.subject.lembDiagnóstico histopatológicospa
dc.subject.lembMedicinaspa
dc.subject.lembEpidemiologíaspa
dc.subject.lembInvestigacionesspa
dc.subject.lembOncológicaspa
dc.description.abstractenglishThe study of bone neoplasms integrates three medical areas: orthopedics, radiology and pathology. The orthopedist begins the study with a complete medical history and physical examination where he generates a first diagnostic impression, later complements his research with conventional and specialized radiology imaging studies (radiography, contrast tomography and magnetic resonance imaging), which allows the characterization of the lesions, define location, contrast characteristics that guide the type of tumor and level of tissue involvement; finally, according to the findings, a biopsy is performed. The biopsy makes it possible to obtain a sample of the musculoskeletal tissues that determine the nature of the lesion to identify malignant or benign lesions, which guides the definitive therapeutic conduct (1). Two routes are used to perform the biopsy: open (excisional or incisional) and percutaneous (or puncture); The latter can be done with a thick needle, either with Tru-Cut or core-type bone needles that extract a cylinder; Fine needle biopsy, also known as BACAF, is very frequently used for carcinomas but in musculoskeletal lesions it is not recommended because it only allows cell analysis without stroma. The decision of the type of biopsy will depend on the location of the lesion, the differential diagnosis and the experience of the pathologist (2). When comparing both procedures, the open biopsy allows obtaining a greater amount of tissue, with greater reliability and precision, however it is a more expensive procedure, it must be performed in operating rooms with an anesthesiologist, it presents a higher risk of fracture, of peripheral tissue involvement , and wound complications such as infections, seromas, hematomas, wound dehiscence, tumor contamination (3,4). Percutaneous biopsy is a minimally invasive procedure, it can be performed in a procedure room, at a lower cost, has lower morbidity with a lower risk of complications, and allows obtaining an adequate amount of tissue to make the diagnosis. However, it requires an experienced pathologist (5). The present study seeks to define the general characteristics of the histopathological findings in percutaneous and open biopsies of an oncology center in orthopedics, as well as to explore risk factors for the conversion of a percutaneous to open biopsy.eng
dc.subject.proposalÁreas medicasspa
dc.subject.proposalHistoria clínicaspa
dc.type.redcolhttp://purl.org/redcol/resource_type/TM
dc.rights.creativecommonsAtribución-NoComercial-SinDerivadas 2.5 Colombia*
dc.coverage.campusUNAB Campus Bucaramangaspa
dc.description.learningmodalityModalidad Presencialspa


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