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dc.contributor.advisorTello Hernández, Alejandro
dc.contributor.advisorCamacho López, Paul Anthony
dc.contributor.authorViteri Solórzano, Eduardo Javier
dc.coverage.spatialSantander, (Colombia)spa
dc.date.accessioned2021-08-23T21:58:25Z
dc.date.available2021-08-23T21:58:25Z
dc.date.issued2020-05-28
dc.identifier.urihttp://hdl.handle.net/20.500.12749/13966
dc.description.abstractLa enfermedad cardiovascular es una de las principales causas de morbimortalidad a nivel global y en Colombia. Actualmente existen diversos métodos para identificar el riesgo cardiovascular a nivel individual que permiten guiar políticas públicas y decisiones clínicas. Sin embargo los métodos no son perfectos y pueden beneficiarse de información adicional para mejorar sus predicciones. Nuevas tecnologías en análisis de imagen de exámenes oftalmológicos actualmente disponibles como la tomografía por coherencia óptica (OCT) permiten un análisis cuantitativo de la microvascularización retiniana. Debido diversos reportes en la literatura que asocian cambios en los plexos vasculares retinianos con presencia o desenlaces de enfermedad cardiovascular se plantea un estudio para analizar si los datos objetivos y cuantificables que ofrece el OCT con angiografía se asocian con otros marcadores individuales o puntuaciones globales de riesgo cardiovascular ya establecidos y que se estudian actualmente en cohortes dentro de la institución. Este análisis observacional realizado por primera vez en nuestro medio busca explorar la existencia de posibles biomarcadores retinianos que brinden información adicionalsobre el riesgo cardiovascular y/o permitan una referencia temprana a servicios especializados.spa
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dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/*
dc.titleCaracterísticas de la microvascularización retiniana y marcadores de riesgo cardiovascularspa
dc.title.translatedCharacteristics of retinal microvascularization and cardiovascular risk markersspa
dc.degree.nameEspecialista en Oftalmologíaspa
dc.publisher.grantorUniversidad Autónoma de Bucaramanga UNABspa
dc.rights.localAbierto (Texto Completo)spa
dc.publisher.facultyFacultad Ciencias de la Saludspa
dc.publisher.programEspecialización en Oftalmologíaspa
dc.description.degreelevelEspecializaciónspa
dc.type.driverinfo:eu-repo/semantics/masterThesis
dc.type.localTesisspa
dc.type.coarhttp://purl.org/coar/resource_type/c_bdcc
dc.subject.keywordsMedical sciencesspa
dc.subject.keywordsHealth sciencesspa
dc.subject.keywordsOphthalmologyspa
dc.subject.keywordsRetinal microvascularizationspa
dc.subject.keywordsCardiovascular diseasespa
dc.subject.keywordsBlood circulation disordersspa
dc.subject.keywordsMedical statisticsspa
dc.subject.keywordsPublic healthspa
dc.subject.keywordsRetinal diseasesspa
dc.identifier.instnameinstname:Universidad Autónoma de Bucaramanga - UNABspa
dc.identifier.reponamereponame:Repositorio Institucional UNABspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersion
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2spa
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dc.contributor.cvlacTello Hernández, Alejandro [0001009125]spa
dc.contributor.cvlacCamacho López, Paul Anthony [0000323578]spa
dc.contributor.googlescholarCamacho López, Paul Anthony [OvqUoOAAAAAJ&hl=es&oi=ao]spa
dc.contributor.orcidTello Hernández, Alejandro [0000-0001-5081-0720]spa
dc.contributor.orcidCamacho López, Paul Anthony [0000-0002-6233-9582]spa
dc.contributor.researchgateTello Hernández, Alejandro [Alejandro-Tello]spa
dc.subject.lembOftalmologíaspa
dc.subject.lembCiencias médicasspa
dc.subject.lembTrastornos de la circulación sanguíneaspa
dc.subject.lembEstadísticas médicasspa
dc.subject.lembSalud públicaspa
dc.subject.lembEnfermedades de la retinaspa
dc.identifier.repourlrepourl:https://repository.unab.edu.cospa
dc.description.abstractenglishCardiovascular disease is one of the main causes of morbidity and mortality globally and in Colombia. Currently there are various methods to identify cardiovascular risk at the individual level that allow guiding public policies and clinical decisions. However the methods are not perfect and you can benefit from additional information to improve your predictions. New technologies in image analysis of ophthalmological examinations currently available such as optical coherence tomography (OCT) allow a quantitative analysis of retinal microvascularization. Due to various reports in the literature that associate changes in the retinal vascular plexuses with the presence or outcomes of cardiovascular disease, a study is proposed to analyze whether the objective and quantifiable data offered by OCT with angiography are associated with other individual markers or global risk scores cardiovascular disease already established and currently being studied in cohorts within the institution. This observational analysis carried out for the first time in our setting seeks to explore the existence of possible retinal biomarkers that provide additional information on cardiovascular risk and / or allow an early referral to specialized services. The World Health Organization (WHO) indicates that cardiovascular disease represents 31% of all causes of death globally. In Colombia, it stands out as the main cause of death and is an important contributor to premature mortality (30-70 years), as in other low- and lower-middle-income countries. In most patients, pathophysiological processes are present long before the disease and the development of simple tests that identify them are useful to define high-risk populations in primary or secondary care. (1) Retinal microvascularization, easily accessible with non-invasive methods, seems to share similar physiological and anatomical characteristics with cerebral and coronary microvascularization (2). The abnormalities of these retinal plexuses could therefore reflect those observed in other vascular beds that are currently recognized as key sites in the pathophysiology of cardiovascular diseases. Optical coherence tomography angiography (OCT-A) allows objective quantification of retinal microvascularization through computerized image analysis. This new diagnostic method is an extension of the capabilities of the software in a widely diffused equipment in current ophthalmology practice. Its use allows estimating the vascular density of retinal capillary beds in an objective and numerical way, which facilitates establishing correlations with ocular or systemic pathologies. Establishing associations between characteristics of the retinal microvasculature obtained by a non- invasive examination and known cardiovascular risk factors for our population may allow ophthalmologists to identify patients at higher risk that merit preventive actions.spa
dc.subject.proposalCiencias de la saludspa
dc.subject.proposalMicrovascularización retinianaspa
dc.subject.proposalEnfermedad cardiovascularspa
dc.type.redcolhttp://purl.org/redcol/resource_type/TM
dc.type.redcolhttp://purl.org/redcol/resource_type/TM
dc.rights.creativecommonsAtribución-NoComercial-SinDerivadas 2.5 Colombia*


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Atribución-NoComercial-SinDerivadas 2.5 Colombia
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