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dc.contributor.advisorVargas Pérez, Oliveriospa
dc.contributor.advisorGalvis, Melquisedecspa
dc.contributor.advisorFerreira, Carlosspa
dc.contributor.advisorValenzuela, Carolinaspa
dc.contributor.advisorOchoa, Miguelspa
dc.contributor.authorMantilla García, Daniel Eduardospa
dc.coverage.spatialColombiaspa
dc.coverage.temporal2014-2019spa
dc.date.accessioned2021-01-29T16:57:19Z
dc.date.available2021-01-29T16:57:19Z
dc.date.issued2020-11
dc.identifier.urihttp://hdl.handle.net/20.500.12749/12082
dc.description.abstractObjetivos: Evaluar el impacto clínico del software de simulación numérica Sim & Size en el tratamiento de pacientes con aneurismas cerebrales saculares no rotos con stents Flow-divering Pipeline. Materiales y métodos: Se realizó un estudio analítico monocéntrico retrospectivo de pacientes tratados por un aneurisma intracraneal mediante la técnica de reconstrucción de la arteria madre con stent desviador de flujo, en la clínica FOSCAL, del 1 de junio de 2014 al 31 de diciembre de 2019. Se evaluaron dos grupos de población: pacientes tratados con y sin el uso del software de simulación numérica intraoperatoria Sim & Size. Se realizaron análisis univariados y bivariados. Resultados: se analizaron 73 registros de intervenciones de 68 pacientes. 56 (76,70%) intervenciones con simulación y 17 (23,30%) sin simulación. En el grupo de simulación, el tiempo quirúrgico fue de 100 minutos (85-125) versus 118 (61-175) en el grupo sin simulación (p = .20). El diámetro del stent fue de 4 mm (3,50- 4,40) y 3,75 mm (3-4) en los pacientes con simulación y sin simulación respectivamente (p = 0,20). La longitud del stent fue de 16 mm (12-20 mm) en los pacientes con simulación y 20 mm (20-20 mm) en el otro grupo (p <0,001). La proporción de stents implantados en un paciente fue de 1,03 frente a 1,13, en el grupo con simulación frente a sin simulación. No hubo tromboembolia inmediata. complicaciones en cualquier grupo. Conclusiones: El uso del software de simulación (Sim & Size®) para el tratamiento endovascular de pacientes con aneurismas cerebrales saculares no rotos reduce el tiempo quirúrgico y la longitud del stent de tubería desviadora de flujo, y la cantidad de dispositivos usados ​​por el paciente.spa
dc.format.mimetypeapplication/pdfspa
dc.language.isospaspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/*
dc.titleImpacto clínico del software de simulación Sim & Size® en el tratamiento de pacientes con aneurismas cerebrales con stents Pipeline desviadores de flujospa
dc.title.translatedClinical impact of Sim & Size® simulation software in the treatment of patients with cerebral aneurysms with flow-diverting Pipeline stentsspa
dc.degree.nameEspecialistas en Radiología e Imágenes Diagnósticasspa
dc.publisher.grantorUniversidad Autónoma de Bucaramanga UNABspa
dc.rights.localAbierto (Texto Completo)spa
dc.publisher.facultyFacultad Ciencias de la Saludspa
dc.publisher.programEspecialización en Radiología e Imágenes Diagnósticasspa
dc.description.degreelevelEspecializaciónspa
dc.type.driverinfo:eu-repo/semantics/masterThesis
dc.type.localTesisspa
dc.type.coarhttp://purl.org/coar/resource_type/c_bdcc
dc.subject.keywordsMedical scienceseng
dc.subject.keywordsHealth scienceseng
dc.subject.keywordsRadiologyeng
dc.subject.keywordsDiagnostic imagingeng
dc.subject.keywordsClinical impacteng
dc.subject.keywordsSimulation softwareeng
dc.subject.keywordsProgramas para computadoreng
dc.subject.keywordsVascular diseaseseng
dc.subject.keywordsAneurysmseng
dc.subject.keywordsMedicine simulationeng
dc.identifier.instnameinstname:Universidad Autónoma de Bucaramanga - UNABspa
dc.identifier.reponamereponame:Repositorio Institucional UNABspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersion
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2spa
dc.relation.references1. Giordan E, Sorenson TJ, Brinjikji W, et al. Risk factors for growth of conservatively managed unruptured intracranial aneurysms. Acta Neurochir. 2018;160(12):2419–23. DOI: 10.1007/s00701-018-3729-zspa
dc.relation.references2. Caroff J, Neki H, Mihalea C, et al. Flow-Diverter Stents for the Treatment of Saccular Middle Cerebral Artery Bifurcation Aneurysms. AJNR Am J Neuroradiol. 2016;37(2):279-84. DOI: https://doi.org/10.3174/ajnr.A4540spa
dc.relation.references3. Altschul D, Vats T, Unda S. Endovascular Treatment of Brain Aneurysms. In: Bozzetto P, Ahmad R, Abdullahi A, eds. New Insight into Cerebrovascular Diseases. First ed. Intechopen; 2020:177-126.spa
dc.relation.references4. Nishimura K, Otani K, Mohamed A, et al. . Accuracy of Length of Virtual Stents in Treatment of Intracranial Wide-Necked Aneurysms. Cardiovasc Intervent Radiol. 2019;42(8):1168-1174. DOI: https://doi.org/10.1007/s00270- 019-02230-9spa
dc.relation.references5. Kühn AL, Wakhloo AK, Gounis MJ, et al. Use of self-expanding stents for better intracranial flow diverter wall apposition. Interv Neuroradiol. 2017;23(2):129–36. Doi: 10.1177/1591019916681981spa
dc.relation.references6. Sim&Cure (Grabels, France). Available: https:// sim- and- cure. com [Accessed 25 May 2020].spa
dc.relation.references7. Giordan E, Sorenson TJ, Brinjikji W, et al. Risk factors for growth of conservatively managed unruptured intracranial aneurysms. Acta Neurochir. 2018;160(12):2419-2423. DOI: 10.1007/s00701-018-3729-z. 2018.spa
dc.relation.references8. Lorenzo Piergallini, Federico Cagnazzo, Giorgio Conte, et al. Virtual simulation with Sim&Size software for Pipeline Flex Embolization: evaluation of the technical and clinical impact. J NeuroIntervent Surg. 2020;0:1–6. DOI:10.1136/neurintsurg-2020-015813spa
dc.relation.references9. Cheung N, Boutchard M, Carr M, et al. Radiation exposure, and procedure and fluoroscopy times in endovascular treatment of intracranial aneurysms: a methodological comparison. J NeuroIntervent Surg 2018;0:1–6. DOI:10.1136/neurintsurg-2017-013596.spa
dc.relation.references10. Hahnemann ML, Ringelstein A, Sandalcioglu IE, et al. Silent embolism after stent-assisted coiling of cerebral aneurysms: diffusion-weighted MRI study of 75 cases. J Neurointerv Surg. 2014;6(6):461-5. DOI: 10.1136/neurintsurg- 2013-010820.spa
dc.relation.references11. Ospel JM, Gascou G, Costalat V, et al. Comparison of Pipeline Embolization Device Sizing Based on Conventional 2D Measurements and Virtual Simulation Using the Sim&Size Software: An Agreement Study. AJNR Am J Neuroradiol. 2019;40(3):524–30. DOI: http://dx.doi.org/10.3174/ajnr.A597spa
dc.relation.references12. Ku¨hn A, Macedo-Rodrigues K, Wakhloo A, et al. Endovascular techniques for achievement of better flow diverter wall apposition. Interv Neuroradiol. 2019;25(3):344-7. DOI: 10.1177/1591019918815294spa
dc.relation.references13. Zhang H, Gao X, Liang H, et al. Incomplete stent apposition of low-profile visualized intraluminal support stents in the treatment of cerebral aneurysms. J Neurointerv Surg. 2020;12(6):591-7. http://dx.doi.org/10.1136/neurintsurg-2019- 015505spa
dc.relation.references14. Marel K, Gounis M, Weaver J, et al. Grading of Regional Apposition after Flow-Diverter Treatment (GRAFT): a comparative evaluation of VasoCT and intravascular OCT. J Neurointerv Surg. 2016;8(8):847-52. DOI: 10.1136/neurintsurg-2015-011843.spa
dc.relation.references15. Salem M, Ravindran K, Enriques-Marulanda A, et al. Pipeline Embolization Device Versus Stent-Assisted Coiling for Intracranial Aneurysm Treatment: A Retrospective Propensity Score-Matched Study. Neurosurgery. 2020;4:nyaa041. DOI: https://doi.org/10.1093/neuros/nyaa041.spa
dc.contributor.cvlachttps://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001765288*
dc.contributor.orcidhttps://orcid.org/0000-0003-3389-711X*
dc.subject.lembCiencias médicasspa
dc.subject.lembRadiologíaspa
dc.subject.lembDiagnóstico para imágenesspa
dc.subject.lembProgramas para computadorspa
dc.subject.lembEnfermedades vascularesspa
dc.subject.lembSimulación medicinaspa
dc.identifier.repourlrepourl:https://repository.unab.edu.cospa
dc.description.abstractenglishObjectives: To evaluate the clinical impact of the Sim & Size numerical simulation software in the treatment of patients with unruptured saccular brain aneurysms with Flow-Diverting Pipeline stents. Materials and methods: A retrospective monocentric analytical study of patients treated for an intracranial aneurysm using the parent artery reconstruction technique with flow diverter stent, at FOSCAL clinic, from June 1st, 2014, to December 31st, 2019 was performed. Two population groups were evaluated: Patients treated with and without the use of Sim&Size intraoperative numerical simulation software. Univariate and bivariate analysis were performed. Results: 73 records of interventions of 68 patients were analyzed. 56 (76.70%) interventions with simulation and 17 (23.30%) without simulation. In the simulation group, surgical time was 100 minutes (85-125) versus 118 (61-175) in the group without simulation (p= .20). The diameter of the stent was 4 mm (3.50- 4.40) and 3.75mm (3-4) in the patients with simulation and without simulation respectively (p= .20). The stent length was 16 mm (12-20mm) in the patients with simulation and 20 mm (20-20mm) in the other group (p <.001). The number proportion of implanted stents for a patient was 1.03 vs 1.13, in the group with simulation vs. without simulation. There were no immediate thromboembolic complications in any group. Conclusions: The use of the simulation software program (Sim & Size®) for the endovascular treatment of patients with unruptured saccular cerebral aneurysms decreases surgical time and the length of the flow-diverting pipeline stent, and the quantity of the used devices for the patient.eng
dc.subject.proposalCiencias de la saludspa
dc.subject.proposalImpacto clínicospa
dc.subject.proposalSoftware de simulaciónspa
dc.subject.proposalAneurismasspa
dc.type.redcolhttp://purl.org/redcol/resource_type/TM
dc.rights.creativecommonsAtribución-NoComercial-SinDerivadas 2.5 Colombia*


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