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Aproximación práctica a la insulinoterapia

dc.contributor.authorRestrepo Vesga, Paolaspa
dc.contributor.authorSandoval Sus, José Davidspa
dc.date.accessioned2020-10-27T14:21:35Z
dc.date.available2020-10-27T14:21:35Z
dc.date.issued2006-04-02
dc.identifier.issn2382-4603
dc.identifier.issn0123-7047
dc.identifier.urihttp://hdl.handle.net/20.500.12749/10403
dc.description.abstractLa diabetes mellitus tipo 2 (DM 2) es una patología de alta prevalencia y gran repercusión a nivel de salud pública, la cual se está diagnosticando tardíamente en su historia natural. Actualmente, se está dando mayor relevancia a la disfunción de la célula beta desde el comienzo de la enfermedad sin dejar de lado la ya conocida resistencia periférica a la insulina. La falla progresiva de estas células pancreáticas lleva a un mal control de los niveles glucémicos con inicio temprano de la insulinoterapia. En el presente artículo se expone de una forma sencilla el papel de la insulinoterapia en la DM2 las indicaciones, métodos de dosificación insulínica, efectos adversos y metas deseadas de control en el paciente diabético.[Restrepo P, Sandoval JD. Aproximación práctica a la insulinoterapia. MedUNAB 2006;9:51-57]spa
dc.format.mimetypeapplication/pdfspa
dc.language.isospaspa
dc.publisherUniversidad Autónoma de Bucaramanga UNAB
dc.relationhttps://revistas.unab.edu.co/index.php/medunab/article/view/168/153
dc.relation.urihttps://revistas.unab.edu.co/index.php/medunab/article/view/168
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/
dc.sourceMedUNAB; Vol. 9 Núm. 1 (2006): Linfocitos B, Mortalidad Evitable, Trastornos del sueño; 51-57
dc.subjectCiencias de la salud
dc.subjectCiencias biomédicas
dc.subjectCiencias de la vida
dc.subjectInnovaciones en salud
dc.subjectInvestigaciones
dc.titleAproximación práctica a la insulinoterapia
dc.title.translatedA practical approach to insulin therapyeng
dc.publisher.facultyFacultad Ciencias de la Salud
dc.publisher.programPregrado Medicina
dc.type.driverinfo:eu-repo/semantics/article
dc.type.localArtículospa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501
dc.subject.keywordsHealth Scienceseng
dc.subject.keywordsMedicineeng
dc.subject.keywordsMedical Scienceseng
dc.subject.keywordsBiomedical Scienceseng
dc.subject.keywordsLife Scienceseng
dc.subject.keywordsInnovations in healtheng
dc.subject.keywordsResearcheng
dc.subject.keywordsDiabetes mellitus type 2
dc.subject.keywordsInsuline
dc.subject.keywordsInsulinotherapy
dc.identifier.instnameinstname:Universidad Autónoma de Bucaramanga UNABspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersion
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.relation.referencesAschner P, et al. Guías ALAD 2000 para el diagnostico y manejo de la diabetes mellitus tipo 2 con medicina basada en el evidencia. Rev Asoc Latinoam Diab 2000; Supl. 1 Ed. Extraordinaria
dc.relation.referencesLeahy J. What is the role for insulin therapy in type 2 diabetes? Curr Op Endocrinol Diabetes 2003; 10:99 -103
dc.relation.referencesHarris MI, Klein R, Welborn TA, et al. Onset of NIDDM occurs at least 4 -7 yrs before clinical diagnosis. Diabetes care 1992; 15: 815 – 9
dc.relation.referencesHarris MI, Flegal KM, Cowie CC, Eberhardt MS et al. Preva-lence of diabetes, impaired fasting glucose and impair glucose tolerance in U.S. adults: the Third National Health and Nutrition examination Survey 1988 -1994. Diabetes care 1998; 21: 518 – 24
dc.relation.referencesWhite J, et al. clarifying the role of insulin in type 2 diabetes management. Clinical diabetes 2003; 21: 14 -21
dc.relation.referencesU.K. Prospective Study Group: Intensive blood – glucose control with sulphonylureas or insulin compared with conventional treat-ment and risk of complications in patients with type 2 diabetes. Lancet 1998; 353: 837 – 53
dc.relation.referencesKoro CE, Bowlin SJ, Bourgeois N, Fedder DO. Glycemic control from 1988 to 2000 among U.S. adults diagnosed with type 2 diabetes: a preliminary report. Diabetes care 2004; 27: 17 -20
dc.relation.referencesMayfield J, White R. Insulin theraoy for type 2 diabetes: Rescue, augmentation, and replacement of beta cell function. Am Fam Physician 2004; 70:489 – 500
dc.relation.referencesKahn SE. The importance of the beta –cell in the pathogenesis of type 2 diabetes mellitus. Am J Med 2000; 108(Suppl 6a): 2S -8
dc.relation.referencesGlaser B, Cerasi E. Early intensive insulin treatment for induction of long –term glycaemic control in type 2 diabetes. Diabetes Obes Metab 1999; 1: 67 -74
dc.relation.referencesPolosky KS, Given BD, Hirsch LJ, Tillil H, et al. Abnormal pat-terns of insulin secretion in non – insulin – dependent diabetes mellitus. N Eng J Med 1988; 318: 1231 - 9
dc.relation.referencesDefronzo RA. Pharmacologic therapy for type 2 diabetes. Ann Intern Med 1999; 131: 281 – 303
dc.relation.referencesLevobitz HE. Oral therapies for diabetic hyperglycemia. Endo-crinol Metab Clin North Am 2001; 30: 909 – 33
dc.relation.referencesYale JF, Valiquett TR, Ghazzi MN, et al. The effect of a thiazo-lidinedione drug, troglitazone, on glycemia in patients with type 2 diabetes poorly control with sulfonylurea and metformina. A multicenter, randomized, double – blind, placebo controlled trial. Ann Inter Med 2001, 134: 737 – 45
dc.relation.referencesHirsch IR, et al. A real world approach to insulin therapy in primary care practice. Clinical diabetes 2005, 23: 78 – 86
dc.relation.referencesThe DCCT Research Group: The effect of intensive treatment of diabetes on the development and progression of long – term complications in insulin-dependent diabetes mellitus. N Eng J Med 1993; 329: 977 – 86
dc.relation.referencesOhkubo Y, et al. Intensive insulin therapy prevents the pro-gression of diabetic microvascular complications in Japanese patients with non-insulin dependent diabetes: a randomized prospective 6-year study. Diabetes Res Clin Pract 1995; 28: 103 – 17
dc.relation.referencesGaede P, et al. Multifactorial intervention and cardiovascular diseases in patients with type 2 diabetes. N Eng J Med 2003; 348: 338 -93
dc.relation.referencesVehkavaara S, et al. Insulin therapy improves endothelial function in type 2 diabetes. Arterioscler Thromb Vasc Biol 2000; 20: 545 -50
dc.relation.referencesRosenfeld L. Insulin: discovery and controversy. Clin Chem 2002; 48: 2270 -88
dc.relation.referencesHirsch IR. Insulin Analogues. N Eng J Med. 2005; 352: 174 -83
dc.relation.referencesDeWitt DE, Hirsch IB. Outpatient insulin therapy in type 1 and type 2 diabetes mellitus. JAMA. 2003; 289: 2254 -64
dc.relation.referencesWard Wk, Bolngiano DC, McKnigth B, Halter JB, Porte D Jr. Diminish B-cell secretory capacity in patients in patients with non – insulin diabetes mellitus. J Clin Invest. 1984; 74: 1318-28
dc.relation.referencesHolleman F. Insulin lispro. N Eng J Med. 1997; 337: 176 –
dc.relation.referencesFreemantke N, et al. Availability of inhaled insulin promotes greater perceived acceptance of insulin therapy in patients with type 2 diabetes. Diabetes care. 2005; 28: 427 -28
dc.relation.referencesLepore M, et al. Pharmacokinetics and pharmacodynamics of subcutaneous injection long-acting human insulin analogue glargine, NPH insulin and ultralente human insulin and conti-nuous subcutaneous infusion of insulin lispro. Diabetes. 2000; 49: 2142 -8
dc.relation.referencesHowey DC, Bowsher RR, Brunelle RL, Woodworth JR. Lyspro human insulin: a rapidly absorbed analogue of human insulin. Diabetes. 1994; 43: 396 – 402
dc.relation.referencesRiddle M, Rosenstock J, Gerich J. The Treat To Target Trial: Randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients. Diabetes care. 2003; 26: 3080 -6
dc.relation.referencesDeFronzo RA, ed. Current therapy of diabetes mellitus. St.Louis: Mosby, 1998: 108-16
dc.relation.referencesBastyr EJ 3d, et al. Therapy focus on lowering postprandial glu-cose, not fasting glucose, may be superior for lowering HbA1c. Diabetes care. 2000; 23: 1236 -41
dc.relation.referencesHope PD, Lindholm A, Hylleberg B, Round P. Improved glycemic control with insulin aspart: a multicenter double – blind crossover trial in type 1 diabetic patients. Diabetes care 1998; 21: 1904 -9
dc.relation.referencesBastyr EJ 3d, et al. Insulin lispro in the treatment of patients with type 2 diabetes mellitus after oral agent failure. Clin Ther. 1999; 21: 1703 -14
dc.relation.referencesHaffner SM, et al. Insulin sensitivity in type 2 diabetic patients: relationship with cardiovascular risk factors: the insulin resis-tance atherosclerosis study. Diabetes care. 1999; 562-8
dc.relation.referencesRaskin P, Rojas P, Allen E. Comparison of twice-daily biphasic insulin apart 70/30 (BIAsp 70/30) with once daily insulin glargine (GLA) in patients with type 2 DM on oral antidiabteic agents. Diabetes. 2004 (Suppl 2); 602-P
dc.relation.referencesPerseghin G, et al. Increase glucose transport – phosphorylation and muscle glycogen synthesis after exercise training insulin – resistance subjects. N Eng J Med. 1996; 335: 1357 – 62
dc.relation.referencesYki-Jarvinein H. Combination therapies with insulin in type 2 diabetes. Diabetes Care. 2001; 24: 758 – 67
dc.relation.referencesYki-Jarvinein H, et al. Comparison of bed time insulin regimens in patients with type 2 diabetes mellitus. A randomized controlled trial. Ann Inter Med. 1999; 130: 389- 96
dc.relation.referencesAmerican Diabetes Association. Standards of medical care for patients with Diabetes Mellitus (Position statement). Diabetes Care. 2005; (Suppl. 1): S4 – 36
dc.subject.lembCiencias médicas
dc.subject.lembMedicina
dc.identifier.repourlrepourl:https://repository.unab.edu.co
dc.description.abstractenglishDiabetes mellitus type 2 (DM 2) is patology of high prevalence and great repercusion in public health, and it ́s been diagnosed late in the natural histoty of the disease. At the moment, it is been given greater relevance to the disfunction of beta cells since the begining of the disease without leaving apart the periferic insulin resistance that is already known. The progresive failure of these pancreatic cells leads to a poor glicemic control with an early use of inslin therapy. In these article it ́s presented in a simple way the function of insulin therapy in DM 2, indications, insulin dosification metods, adverse effects and wished goals for glicemic control in diabetic patients. [Restrepo P, Sandoval JS.Practical approach to insulinotherapy. MedUNAB 2006; 9:51-57eng
dc.subject.proposalDiabetes Mellitus tipo 2
dc.subject.proposalInsulina
dc.subject.proposalInsulinoterapia
dc.type.redcolhttp://purl.org/redcol/resource_type/ART


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