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Arteritis de Nissl en sífilis meningovascular y falla terapéutica con ceftriaxona. Informe de un caso y revisión en la literatura
dc.contributor.author | Montes, María Isabel | spa |
dc.contributor.author | Millán, Paula Andrea | spa |
dc.contributor.author | Uribe, Carlos Santiago | spa |
dc.date.accessioned | 2020-10-27T14:21:32Z | |
dc.date.available | 2020-10-27T14:21:32Z | |
dc.date.issued | 2006-08-06 | |
dc.identifier.issn | 2382-4603 | |
dc.identifier.issn | 0123-7047 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12749/10396 | |
dc.description.abstract | Presentamos el caso clínico de un paciente de 45 años, VIH negativo, con enfermedad cerebro-vascular recurrente secundaria a neurosífilis meningovascular y falla terapéutica con ceftriaxona. La neurosífilis es el compromiso del sistema nervioso central por el Treponema pallidum en cualquier estadio de la entidad, e incluye tanto las formas asintomáticas y sintomáticas de la infección; sus formas de presentación son diversas y dependen de la localización y la extensión de las lesiones. Las imágenes de resonancia magnética de encéfalo muestran múltiples lesiones vasculíticas que reflejan el compromiso de pequeño vaso (arteritis de Nissl) ocasionadas por el treponema. La recomendación actual del tratamiento es con penicilina cristalina 4 millones cada 4 horas por 14 días. La evidencia hasta el momento en personas VIH positivas que presentan sífilis latente con o sin neurosífilis, tratadas con ceftriaxona, ha mostrado hasta un 23% de falla terapéutica, se carece de información en pacientes inmunocompetentes. [Montes MI, Millán PA, Uribe CS. Arteritis de Nissl en sífilis meningovascular y falla terapéutica con ceftriaxona. Informe de un caso y revisión en la literatura. MedUNAB 2006; 9: 174-178]. | spa |
dc.format.mimetype | application/pdf | spa |
dc.language.iso | spa | spa |
dc.publisher | Universidad Autónoma de Bucaramanga UNAB | |
dc.relation | https://revistas.unab.edu.co/index.php/medunab/article/view/162/147 | |
dc.relation.uri | https://revistas.unab.edu.co/index.php/medunab/article/view/162 | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/2.5/co/ | |
dc.source | MedUNAB; Vol. 9 Núm. 2 (2006): Imágenes Diagnósticas; 174-178 | |
dc.subject | Ciencias médicas | |
dc.subject | Ciencias biomédicas | |
dc.subject | Ciencias de la vida | |
dc.subject | Innovaciones en salud | |
dc.subject | Investigaciones | |
dc.title | Arteritis de Nissl en sífilis meningovascular y falla terapéutica con ceftriaxona. Informe de un caso y revisión en la literatura | |
dc.title.translated | Nissl's arteritis in meningovascular syphilis and therapeutic failure with ceftriaxone. Report of a case and review in the literature | eng |
dc.publisher.faculty | Facultad Ciencias de la Salud | |
dc.publisher.program | Pregrado Medicina | |
dc.type.driver | info:eu-repo/semantics/article | |
dc.type.local | Artículo | spa |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | |
dc.subject.keywords | Health Sciences | eng |
dc.subject.keywords | Medicine | eng |
dc.subject.keywords | Medical Sciences | eng |
dc.subject.keywords | Biomedical Sciences | eng |
dc.subject.keywords | Life Sciences | eng |
dc.subject.keywords | Innovations in health | eng |
dc.subject.keywords | Research | eng |
dc.subject.keywords | Meningovascular syphilis | |
dc.subject.keywords | Nissl arteritis | |
dc.subject.keywords | Crystalline penicillin | |
dc.subject.keywords | Ceftriaxone | |
dc.identifier.instname | instname:Universidad Autónoma de Bucaramanga UNAB | spa |
dc.type.hasversion | info:eu-repo/semantics/acceptedVersion | |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
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dc.relation.references | Uribe CS, Arana A, Borrego C, Cornejo W. Estudio clínico y sero-lógico de 22 pacientes con sífilis del sistema nervioso central. Acta Med Colomb 1985; 10:1259 | |
dc.relation.references | Conde-Sendin M, Hernández J, Cardenes-Santana M, Amela-Peris R. Neurosífilis: formas de presentación y manejo clinico. Rev Neurol 2002; 35:380-86 | |
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dc.relation.references | Hook EW. Syphilis. In: Scheld WM, Whitley RJ, Durak DT. Infec-tions of central nervous system. Philadelphia, Lippicott Raven, 2 ed, 1997:669-84 | |
dc.relation.references | Brightbill TC, Ihmeidan IH, Donovan Post MJ, Berger JR, Katz DA. Neurosyphilis in HIV positive and HIV negative patients: neuroimaging findings. Am J Neuroradiol 1995;16:703-11 | |
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dc.relation.references | Tramont DE. Treponema pallidum (Syphilis). Mandel J, Douglas, Bennett J. Dolin E. Principles and practice of infectious diseases. New York, Churchill Livingstone, 4 ed, 1994: 2117-333 | |
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dc.relation.references | French P. Syphilis guidelines revision group. UK national guide-lines for the management of late syphilis 2002. In: http://www.guideline.gov/summary/summary.aspx?doc_id=3037. Con-sulted: June 24, 2006 | |
dc.relation.references | Mohr J, Griffiths W, Jackson R, Saadah H, Bird P, Riddle J. Neurosyphilis and penicillin levels in the cerebrospinal fluid. JAMA 1976; 236:2208-9 | |
dc.relation.references | Johnson RC, Bey RF, Wolgamot SJ. Comparison of the ac-tivities of ceftriaxone and penicillin G against experimentally induced syphilis in rabbits. Animicrob Agents Chemother 1982; 21:984-9 | |
dc.relation.references | Gentile JH, Viviani C, Sparo MD, Arduino RC. Syphilitic menin-gomyelitis treated with ceftriaxone: case report. Clin Infect Dis 1998; 26:528 | |
dc.relation.references | Marra CM, Boutin P, McArthur JC, Hurwitz S, Simpson PA, Haslett JA, et al. A pilot study evaluating ceftriaxone and penicillin G as treatment agents for neurosyphilis in human immunodeficiency virus-infected individuals. Clin Infect Dis 2000; 30:540-4 | |
dc.relation.references | Dowell ME, Ross PG, Musher DM, Cate TR, Baughn RE. Re-sponse of latent syphilis or neurosyphilis to ceftriaxone therapy in persons infected with the human immunodeficiency virus. Am J Med1992; 93:481-8 | |
dc.subject.lemb | Ciencias de la salud | |
dc.subject.lemb | Medicina | |
dc.identifier.repourl | repourl:https://repository.unab.edu.co | |
dc.description.abstractenglish | The authors report a case of a 45 year old patient, negative VIH, with recurrent stroke, secondary to meningovascular syphilis and therapeutic failure with ceftriaxone. The neurosyphilis is due to im-pairment of the nervous central system for the Treponema pallidumin any stadium of the condition, and includes both asymptomatic and symptomatic forms of the infection. The forms of presentation are diverse and depend of the location and extension of the lesions. The MRI shown multiple vascular injuries which reflects the impairment of small blood vessels (Nissl arteritis) caused by the Treponema .The current recommendation of the treatment is with crystalline penicillin G intravenously 4 millions every 4 hours for 14 days. The evidence up to the present time in people’s positive VIH with latent syphilis with or without neurosyphilis treated with ceftriaxone has showned up to 23% of therapeutic failures. There is a lack of information in immunocompetent patients. [Montes MI, Millán PA, Uribe CS. Nissl arteritis in meningovascular syphilis and ceftriaxone therapeutic failure. Case report and review. MedUNAB 2006; 9: 174-178] | eng |
dc.subject.proposal | Sífilis meningovascular | |
dc.subject.proposal | Arteritis de Nissl | |
dc.subject.proposal | Penicilina cristalina | |
dc.subject.proposal | Ceftriaxona | |
dc.type.redcol | http://purl.org/redcol/resource_type/ART | |
dc.rights.creativecommons | Atribución-NoComercial-SinDerivadas 2.5 Colombia | * |
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